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Anti-thyroid drugs can trigger asthma Medications to control an overactive thyroid gland can worsen asthma in co-morbid patients. Dr Rosa Grembiale and colleagues from the University of Catanzaro, Italy, reported the case of a 67-year-old woman who suffered from a severe asthma exacerbation as a consequence of an symptoms of exercise induced asthma symptoms of exercise induced asthma antithyroid drug treatment. The asthmatic patient was referred to the hospital in 1998 because of dry cough, progressive breathlessness, and wheezing, following commencement of antithyroid treatment with methimazole for her enlarged thyroid gland, which had recently become hyper-functioning. Pulmonary function tests showed a reversible obstructive pattern. Therapy with higher doses of inhaled breeds of dogs asthma symptoms of exercise induced asthma corticosteroids and bronchodilators was prescribed, and a follow-up visit was planned after 4 weeks. Despite treatment, symptoms and FEV1 worsened. The patient was admitted to hospital for further investigation and treatment. Differential blood cell count showed a sharp increase in the eosinophil number. The researchers hypothesized that methimazole treatment could have been carpeting and asthma symptoms of exercise induced asthma involved in the pathogenesis of this asthma exacerbation and decided to stop it. Two weeks after stopping methimazole treatment, the patient showed a dramatic improvement in symptoms and pulmonary function, with eosinophil count returning to normal. The researchers said that the methimazole-induced bronchial hypereosinophilia might have caused an exacerbation of asthma, unresponsive symptoms of exercise induced asthma symptoms of exercise induced asthma to bronchodilators.