Asthma and allergy unrelated to CCR5?32 mutation The development of asthma and the presence of atopy are unrelated to the CCR5?32 deletion mutation, report Hungarian researchers. An association between the CCR5?32 allele and protection against asthma had been previously reported in a Scottish study, prompting Dr A Nagy and colleagues from asthma and hockey asthma and hockey the Paediatric Hospital of Budapest to investigate the presence of the allele in 118 children with asthma, 145 with atopy but no asthmatic symptoms and 303 children with neither asthma nor atopy. Blood samples were obtained from all participants, with parental consent, and were tested for white blood cell counts and eosinophil cell counts. The medical risk factors of asthma asthma and hockey CCR5 gene was genotyped and the results analysed with reference to allelic frequency and presence or absence of asthma or atopy. The frequency of the CCR5?32 mutation was, on average, 11.4 per cent among asthmatic children, 11 per cent among non-asthmatic children with atopy and 11.2 per cent among control children with neither condition. Dr remedies bronchial asthma and hockey Nagy and colleagues concluded that, in contrast to the previous study, no variation in prevalence of this allele exists in Hungarian children, and that it does not confer any protection against asthma. The variation in outcome of this and earlier research may suggest that the CCR5?32 allele is protective in some populations but not in herbs to cure asthma asthma and hockey others, they add.
